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Medications and Nutrition A Quick Reference for Busy Clinicians

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Are you a lovely health professional concerned about the impact of prescribed drugs on the nutritional health of the people in your care – and find it difficult and time-consuming to locate good quality, clinically-useful research?

We have developed resources to address frustrations such as yours.

In fact our key resource is a subscription service to an online database that addresses many of the following issues:

  • Altered drug absorption dynamics. Examples include concurrent administration of calcium supplements with levodopa reduces availability of levodopa dose.
  • Altered nutrient absorption dynamics. For example acid-inhibiting drugs alter gastric acidity and decrease absorption of vitamin C.
  • Altered nutrient excretion dynamics. For example digoxin increases magnesium excretion via the kidneys.
  • Impacts of side effects. For example some statins negatively impact appetite with ongoing loss of weight as the outcome.
  • Impacts of specific nutrient supplements. For example iron supplements alter gut microbiota in favour of pathogens.
  • Potential excipient harm. Excipients (the ingredients mixed with the active ingredient) may cause harm for those with specific food allergies and intolerances such as gluten, lactose, galactose, phenylalanine.
  • Non-compliance with drug manufacturers’ administration recommendations. This is particularly relevant to those with impaired swallow reflex or to those requiring enteral feeding. Alteration in drug form or delivery format potentially alters rate and extent of drug effect.
  • Nutrient derivatives as drugs. The impact of the nutrient-derivative drugs on their base nutrient status and metabolism remains unknown, and it is also unknown whether the base nutrients interact with the same drugs that the nutrient-derivative drugs interact with. For example methotrexate is a folic acid derivative – does folic acid interact with the same drugs as methotrexate?
  • Inconsistent drug-food interaction advice. Examples include advice to abstain from alcohol intake whilst consuming antibiotics and yet there is an extensive range of drugs whereby alcohol intake is contra-indicated and the advice to abstain is not highlighted; a low-salt diet is no longer advised if prescribed antihypertensives, and yet a low salt-diet is associated with a smaller drug dose, fewer side effects and lower cost.
Our resources have been developed to support busy clinicians in integrating the impact of drug-nutrition interactions into their day-to-day clinical practice - choose a product that suits you!



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